Stage-Specific Sampling by Pattern Recognition Receptors during Candida albicans Phagocytosis
نویسندگان
چکیده
منابع مشابه
Stage-Specific Sampling by Pattern Recognition Receptors during Candida albicans Phagocytosis
Candida albicans is a medically important pathogen, and recognition by innate immune cells is critical for its clearance. Although a number of pattern recognition receptors have been shown to be involved in recognition and phagocytosis of this fungus, the relative role of these receptors has not been formally examined. In this paper, we have investigated the contribution of the mannose receptor...
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Candida albicans is a major life-threatening human fungal pathogen. Host defence against systemic Candida infection relies mainly on phagocytosis of fungal cells by cells of the innate immune system. In this study, we have employed video microscopy, coupled with sophisticated image analysis tools, to assess the contribution of distinct C. albicans cell wall components and yeast-hypha morphogene...
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Recognition of Candida albicans is mediated by several classes of pattern-recognition receptors, including Toll-like receptors and C-type lectin receptors. Cell wall components of C. albicans, interact with the pattern-recognition receptors, which are expressed by different cells, primarily antigen-presenting cells. This review aims to discuss the different pattern-recognition receptors respons...
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ژورنال
عنوان ژورنال: PLoS Pathogens
سال: 2008
ISSN: 1553-7374
DOI: 10.1371/journal.ppat.1000218